Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors.
نویسنده
چکیده
1. Electron Donor 2223 2. Electron Transfer Path 2225 3. Electron Transfer Mechanism 2226 4. Physiological Relevance 2226 D. Radical Reactions in Photolyase 2226 E. “Dark Function” of Photolyase 2227 F. Regulation of Photolyase 2227 III. (6−4) Photolyase 2228 IV. Cryptochromes 2230 A. Structure 2231 B. Function 2231 1. Circadian Rythm 2231 2. Mammalian Circadian System 2231 3. Cryptochromes and the Circadian Clock 2232 V. Perspectives 2234 VI. Acknowledgment 2235 VII. References 2235
منابع مشابه
Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Signals generated by cryptochrome (CRY) blue-light photoreceptors are responsible for a variety of developmental and circadian responses in plants. The CRYs are also identified as circadian blue-light photoreceptors in Drosophila and components of the mammalian circadian clock. These flavoproteins all have an N-terminal domain that is similar to photolyase, and most have an additional C-termina...
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Cryptochrome (Cry) photoreceptors share high sequence and structural similarity with DNA repair enzyme DNA-photolyase and carry the same flavin cofactor. Accordingly, DNA-photolyase was considered a model system for the light activation process of cryptochromes. In line with this view were recent spectroscopic studies on cryptochromes of the CryDASH subfamily that showed photoreduction of the f...
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ورودعنوان ژورنال:
- Chemical reviews
دوره 103 6 شماره
صفحات -
تاریخ انتشار 2003